Depression Treatment with Ketamine Therapy in Indianapolis
Rediscover Hope with Fast-Acting, Evidence-Based Care
Ketamine can be an effective, fast-acting treatment for severe, treatment-resistant depression or depression with suicidal ideation, often helping when conventional antidepressants fail.
Key Considerations for Ketamine Therapy:
Studies consistently show that a single intravenous (IV) infusion of ketamine can produce a response (defined as a 50% or greater reduction in depression scores) in 50% to 70% of patients, with effects often appearing within hours.
Key Considerations for Ketamine Therapy:
Backed by Clinical Research and Real-World Results
Ketamine is not a traditional antidepressant. It works on a different brain pathway, modulating glutamate receptors, to reset mood and thought patterns quickly.
- Who it is For:
Candidates often include those who have not responded to at least two standard antidepressant trials. It is used for major depression, bipolar depression, and, notably, in reducing suicidal thoughts.
- How it Works:
Administered via intravenous (IV) infusion can provide relief within hours or days.
- Duration:
The effects may be temporary. Initial treatment involves a series of sessions, often followed by maintenance sessions to prevent relapse.
- Risks & Exclusions:
It may not be suitable for individuals with active psychosis, uncontrolled high blood pressure, aneurysms, or certain bladder conditions.
Sources: British Journal of Psychiatry, Vanderbilt University, MDPI, FDA data
Clinical Evidence
Explore peer-reviewed clinical research on the use of ketamine as a treatment for depression, highlighting its rapid-acting therapeutic potential.
Initial (Induction) Phase
The first phase of treatment is an intensive, “loading dose” period designed to achieve initial symptom reduction or remission. On average, after 6 treatments, some patients will achieve remission—defined as a complete resolution of symptoms, often accompanied by a return to normal functioning. Most patients will achieve significant symptom reduction, which can greatly improve quality of life and day-to-day functioning.
Maintenance Phase (Durability)
After the initial induction phase, the patient will know if ketamine has made a dramatic improvement in their quality of life and symptom resolution has been obtained. If so, the patient will then need periodical boosters as needed. Typically these can be as frequent as every 2–4 weeks to once every 3 months. This phase is usually detected after the 5th or 6th infusion for almost everyone. If remission is not obtained by infusion 6, then the provider will reassess the appropriateness of any additional infusions.
Ketamine infusions DO NOT work for everyone. They are costly and require a strong commitment from the patient to follow through with care. This includes attending follow-ups, engaging in therapy, and maintaining open communication with the provider. Some patients may taper off, while others benefit from ongoing boosters. The focus is on maintaining results and adjusting the care plan as needed.
Why Choose Bridgeway to Treat Your Depression?
Ketamine therapy may be ideal if you:
- Evidence-Based Guided Ketamine Therapy
- Physician-Led, Medically Supervised Care
- An Option for Treatment-Resistant Depression
Bridgeway provides a personalized consultation to determine if Ketamine is a safe and effective fit for your needs.
What to Expect at Bridgeway
A Calming, Private Experience Tailored to You
From your first visit, we prioritize comfort, clarity, and compassionate care. Here’s what a typical depression treatment plan looks like:
- Calm, private setting: Comfortable environment in our Indianapolis clinic.
- 45–60 Minute Sessions: Each Ketamine session is carefully timed for optimal results.
- Medical Monitoring: One-on-one monitoring by our medical professionals.
- Treatment Schedule: 6 infusions over 2–3 weeks, with maintenance as needed.
We also integrate emotional support and follow-up care to help you sustain results beyond the infusions.
FAQs About Ketamine for Depression
How does Ketamine help with depression?
Ketamine enhances neuroplasticity and repairs broken mood circuits in the brain. This helps lift depressive symptoms quickly, even in people who haven’t responded to traditional meds.
Is Ketamine treatment safe?
Yes. When administered in a medical setting like Bridgeway, Ketamine is safe and well-tolerated. Side effects like mild dissociation or dizziness are temporary and closely monitored.
How quickly will I feel results?
Many patients feel a shift within 1–3 sessions. The full benefit often emerges after the initial treatment series.
Is this treatment covered by insurance?
Ketamine therapy is typically not covered by insurance, but we offer affordable self-pay packages and help with out-of-network documentation.
Who will oversee my care?
Bridgeway was founded by an experienced CRNA with a mission to serve Veterans and civilians. Every session is supervised by trained, compassionate healthcare providers.