If traditional depression treatments have not provided the results you were hoping for, ketamine therapy may be worth exploring as an alternative treatment option.
Bridgeway provides ketamine therapy for treatment-resistant depression in Indianapolis.
Is Ketamine Therapy Right for Your Depression?
- Who it is For:
Candidates often include those who have not responded to at least two standard antidepressant trials. It is used for major depression, bipolar depression, and notably, in reducing suicidal thoughts.
Research has also examined ketamine’s effect on suicidal ideation. In a randomized clinical trial involving adults with major depression and clinically significant suicidal ideation, ketamine produced a greater reduction in suicidal-ideation scores at 24 hours than midazolam. Ketamine treatment is not a substitute for emergency psychiatric care.
If you are in immediate danger or believe you may harm yourself or someone else, call 911 or go to the nearest emergency department. For 24/7 crisis support in the United States, call or text 988. Bridgeway’s consultation form is not an emergency service. ⁹
- How it Works:Ketamine is administered through an intravenous (IV) infusion in a medically supervised setting. Some patients may experience improvement in depressive symptoms within 24 hours, although individual response varies.³
- Duration:Treatment typically begins with a series of infusions. Because the effects may be temporary for some patients, maintenance sessions may be recommended based on individual response and treatment needs.⁴
- Risks & Exclusions:It may not be suitable for individuals with active psychosis, uncontrolled high blood pressure, aneurysms, or certain bladder conditions.
In one randomized study of adults with treatment-resistant major depression, 64% of participants receiving ketamine met the study’s response criteria at 24 hours, compared with 28% receiving midazolam. Individual response and duration of benefit vary. ³
In one study of repeated IV ketamine infusions for treatment-resistant depression, 59% of participants met the study’s response criteria after the series of infusions. Among participants who responded, the median time to response was three infusions. Individual results vary. ⁴
A randomized study found a greater reduction in suicidal-ideation scores 24 hours after ketamine than after midazolam. This finding does not mean ketamine prevents suicide. ⁵
Why Choose Bridgeway for Depression Treatment in Indianapolis?
- Affordable ketamine therapy starting at $200 per infusion with annual plans available for $3,000/year.
- Physician-Led, Medically supervised IV treatment.
- Physician-Guided Care Informed by Clinical Research Ketamine Therapy.
Experience working with treatment-resistant depression.
Important Treatment Information:
Ketamine is FDA-approved as an anesthetic.1 The use of IV ketamine for depression and chronic pain is off-label and is not an FDA-approved indication for ketamine injection. Treatment is not appropriate for everyone. Potential benefits, risks, alternatives and expected outcomes should be discussed with a qualified medical provider.


